Gabapentin

Gabapentin
source: medicalnewstoday.com

Bagikan :

Brand/nama lain

Alpentin, Nepatic, Epiven, Neurontin, Gabapentin, Neurontin, Gabexal, Sipentin, Ganin.

 

Cara Kerja

Gabapentin adalah obat yang memiliki efek mirip atau agonis gamma-aminobutyric acid (GABA). Obat ini dapat digunakan untuk terapi epilepsi, serta memiliki efek mengurangi nyeri. Selain itu, obat ini dapat mencegah kematian saraf pada penyakit Amyotrophic Lateral Sclerosis (ALS).

Baca lebih lanjut Penyakit Amyotrophic Lateral Sclerosis (ALS).

Gabapentin berinteraksi dengan sel saraf yang sensitif terhadap kalsium, serta dapat masuk ke sel melalui membran lipid. Pada hewan percobaan, gabapentin memiliki efek penghambat kejang. Meski demikian, pada manusia, efek gabapentin sebagai obat kejang masih belum diketahui dengan pasti.

                 

Indikasi

Gabapentin diindikasikan pada pasien dengan epilepsi, nyeri neuropatik, neuralgia pasca herpes.

 

Kontraindikasi

Gabapentin dikontraindikasikan pada pasien yang memiliki riwayat alergi atau hipersensitivitas pada obat ini.

                                                                                                                                                                                                               

Efek Samping

Efek samping dapat terjadi pada kondisi tertentu pada penggunaan gabapentin. Berikut ini merupakan efek samping yang dapat terjadi pada penggunaan gabapentin:

  • anafilaksis,
  • angioedema,
  • ide dan perilaku bunuh diri,
  • pankreatitis akut,
  • timbulnya jenis kejang baru,
  • peningkatan frekuensi kejang,
  • pusing,
  • mengantuk,
  • kebingungan,
  • gangguan mental,
  • penyalahgunaan dan ketergantungan obat,
  • gejala putus obat;
  • reaksi neuropsikiatri (misalnya labilitas emosional, gangguan pikiran, hiperkinesia) pada anak-anak

Penggunaan gabapentin  juga dapat menyebabkan gangguan pada beberapa organ penggunanya. Berikut ini gangguan yang dapat terjadi pada penggunaan gabapentin:

  • Gangguan sistem darah dan limfatik: Leukopenia.
  • Gangguan telinga dan sistem keseimbangan: Otitis media, vertigo.
  • Gangguan mata: Gangguan penglihatan (misalnya ambliopia, diplopia).
  • Gangguan gastrointestinal: Mual, muntah, diare, sakit perut, mulut atau tenggorokan kering, perut kembung, dispepsia, sembelit, kelainan gigi, radang gusi.
  • Gangguan umum dan kondisi tempat pemberian: Demam, kelelahan, asthenia, nyeri, edema perifer, gaya berjalan abnormal, sindrom flu, patah tulang.
  • Infeksi dan infestasi: Infeksi virus.
  • Cedera, keracunan dan komplikasi prosedural: Cedera tidak disengaja.
  • Gangguan metabolisme dan nutrisi: Anoreksia, nafsu makan meningkat.
  • Gangguan muskuloskeletal dan jaringan ikat: Artralgia, mialgia, kedutan, nyeri punggung.
  • Gangguan sistem saraf: Sakit kepala, ataksia, amnesia, disartria, sensasi abnormal (misalnya parestesia), tremor, koordinasi abnormal, nistagmus, refleks abnormal (misalnya meningkat, menurun, atau tidak ada), pemikiran abnormal.
  • Gangguan kejiwaan: Kecemasan, depresi, insomnia, gugup.
  • Gangguan ginjal dan saluran kemih: ISK.
  • Gangguan sistem reproduksi dan payudara: Impotensi.
  • Gangguan pernapasan, toraks, dan mediastinum: Pneumonia, infeksi saluran pernapasan, sesak napas, bronkitis, faringitis, batuk, rinitis.
  • Gangguan kulit dan jaringan subkutan: Ruam, pruritus, jerawat, purpura, abrasi.
  • Gangguan vaskular: Hipertensi, vasodilatasi.

 

Sediaan

Kapsul 100 mg, 300 mg

 

Dosis

Pengobatan epilepsi

Dewasa: 300 mg sekali sehari pada hari ke-1, 300 mg dua kali sehari pada hari ke-2, 300 mg tiga kali sehari pada hari ke-3. Tergantung pada respon pasien terhadap obat, dosis dapat ditingkatkan 300 mg setiap 2 sampai 3 hari. Secara umum, ambil 900 hingga 3.000 mg sehari dalam 3 dosis terbagi.

Anak 6 tahun: dosis awal 10-15 mg/kg. Dosis dapat ditingkatkan setiap 3 hari sampai dosis efektif tercapai. Dosis maksimum adalah 50 mg/kg berat badan.

 

Neuralgia pasca herpes

Dewasa: 300 mg sekali sehari pada hari ke-1, 300 mg setiap 12 jam pada hari ke-2, 300 mg setiap 8 jam pada hari ke-3. Dosis selanjutnya dapat ditingkatkan sesuai kebutuhan hingga 600 mg setiap 8 jam.

 

Keamanan

Ibu hamil:

Kategori C (Penelitian pada binatang percobaan memperlihatkan adanya efek samping terhadap janin, namun belum ada studi terkontrol pada wanita hamil). Obat ini hanya boleh digunakan apabila manfaat yang diharapkan lebih besar dari risiko.

 

Ibu menyusui :

Gabapentin dapat terserap kedalam ASI atau tidak. Obat ini tidak boleh digunakan tanpa konsultasi dan persetujuan dokter

 

Interaksi Obat

Obat ini dapat mengalami penurunan bioavabilitas jika digunakan dengan antasida dan menyebabkan depresi pernafasan dan sistem saraf pusat apabila digunakan dengan golongan CNS depressants (seperti opioid, benzodiazepine, antidepresan dan antihistamin).

 

Mau tahu informasi seputar obat-obatan lainnya? Cek di sini, ya!

Writer : dr Arifin Muhammad Siregar
Editor :
  • dr Ayu Munawaroh, MKK
Last Updated : Jumat, 14 April 2023 | 23:25

Pusat Informasi Obat Nasional. (2022).Monografi- Gabapentin Retrieved 23 September 2022, from https://pionas.pom.go.id/monografi/gabapentin

MIMS Indonesia. (2022). Gabapentin: Indication, Dosage, Side Effect, Precaution. Retrieved 23 September 2022, from h https://www.mims.com/malaysia/drug/info/gabapentin?mtype=generic

National Center for Biotechnology Information (2022). PubChem Compound Summary for CID 3446, Gabapentin. Retrieved September 26, 2022 from https://pubchem.ncbi.nlm.nih.gov/compound/Gabapentin.

Clinical Key . (2022). Drug monograph-  Gabapentin. Retrieved 23 September 2022, from https://www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-271

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  • warninglog[00:32:49] LOG.warning: str_contains(): Passing null to parameter #1 ($haystack) of type string is d...
  • warninglog[00:32:49] LOG.warning: str_contains(): Passing null to parameter #1 ($haystack) of type string is d...
  • infolog[00:32:50] LOG.info: Attempting to authenticate with: { "username": "administrator", "url": ...
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      Backtrace
      • vendor/spatie/laravel-activitylog/src/ActivityLogger.php:174
      • vendor/spatie/laravel-activitylog/src/Traits/LogsActivity.php:88
      • app/Http/Controllers/WebController.php:402
      • vendor/laravel/framework/src/Illuminate/Routing/Controller.php:54
      • vendor/laravel/framework/src/Illuminate/Routing/ControllerDispatcher.php:43
    • single-post-healthpedia.blade.php#37mydatabase830μsselect * from `users` where `users`.`id` = 45 limit 1
      Bindings
      • 0: 45
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.single-post-healthpedia:37
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase8.08msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5030 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5030
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase7.87msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 1638 and `categories`.`deleted_at` is null
      Bindings
      • 0: 1638
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase8.08msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5014 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5014
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase7.87msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5129 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5129
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase8.01msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4986 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4986
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.94msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 5997 and `categories`.`deleted_at` is null
      Bindings
      • 0: 5997
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.93msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 10146 and `categories`.`deleted_at` is null
      Bindings
      • 0: 10146
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.97msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 2818 and `categories`.`deleted_at` is null
      Bindings
      • 0: 2818
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.95msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 4841 and `categories`.`deleted_at` is null
      Bindings
      • 0: 4841
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.97msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 2112 and `categories`.`deleted_at` is null
      Bindings
      • 0: 2112
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.94msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 10350 and `categories`.`deleted_at` is null
      Bindings
      • 0: 10350
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase7.7msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 10035 and `categories`.`deleted_at` is null
      Bindings
      • 0: 10035
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#111mydatabase1.39msselect * from `pages` where `slug` = 'about-us' limit 1
      Bindings
      • 0: about-us
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:111
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#53mydatabase690μsselect * from `categories` where `name` = 'Penyakit A-Z' and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: Penyakit A-Z
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.menu_hover:53
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#54mydatabase610μsselect * from `categories` where `name` = 'Obat A-Z' and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: Obat A-Z
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.menu_hover:54
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#55mydatabase830μsselect * from `categories` where `name` = 'Pemeriksaan A-Z' and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: Pemeriksaan A-Z
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.menu_hover:55
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#156mydatabase2.61msselect * from `videos` where `status` = 1 order by `updated_at` desc limit 1
      Bindings
      • 0: 1
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::layouts.v2.menu_hover:156
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#221mydatabase1.09msselect * from `booklets` where `is_published` = 1 order by `id` desc limit 1
      Bindings
      • 0: 1
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::layouts.v2.menu_hover:221
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#357mydatabase950μsselect * from `faqs` limit 1
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:357
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#361mydatabase2.12msselect * from `term_policies`
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:361
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    App\Models\Admin\Post
    31Post.php#?
    App\Models\Admin\Category
    24Category.php#?
    App\Models\Admin\Tag
    5Tag.php#?
    App\User
    3User.php#?
    App\Models\TermPolicy
    3TermPolicy.php#?
    App\Models\Admin\Healthpedia
    1Healthpedia.php#?
    App\Models\Admin\Page
    1Page.php#?
    App\Models\Admin\Video
    1Video.php#?
    App\Models\Admin\Booklet
    1Booklet.php#?
    App\Models\Admin\Faq
    1Faq.php#?
        locale
        id
        _token
        d0Tb4dhpFJAm2Z7NKd09bOIf95bFHGmTLEp55SZ5
        _previous
        array:1 [ "url" => "https://ai-care-dict.atmatech.id/healthpedia-obat/gabapentin" ]
        _flash
        array:2 [ "old" => [] "new" => [] ]
        path_info
        /healthpedia-obat/gabapentin
        status_code
        200
        
        status_text
        OK
        format
        html
        content_type
        text/html; charset=UTF-8
        request_query
        []
        
        request_request
        []
        
        request_headers
        0 of 0
        array:19 [ "accept-encoding" => array:1 [ 0 => "gzip, deflate, br, zstd" ] "sec-fetch-dest" => array:1 [ 0 => "document" ] "sec-fetch-user" => array:1 [ 0 => "?1" ] "sec-fetch-mode" => array:1 [ 0 => "navigate" ] "sec-fetch-site" => array:1 [ 0 => "none" ] "accept" => array:1 [ 0 => "text/html,application/xhtml+xml,application/xml;q=0.9,image/avif,image/webp,image/apng,*/*;q=0.8,application/signed-exchange;v=b3;q=0.7" ] "user-agent" => array:1 [ 0 => "Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)" ] "upgrade-insecure-requests" => array:1 [ 0 => "1" ] "sec-ch-ua-platform" => array:1 [ 0 => ""Windows"" ] "sec-ch-ua-mobile" => array:1 [ 0 => "?0" ] "sec-ch-ua" => array:1 [ 0 => ""Chromium";v="130", "HeadlessChrome";v="130", "Not?A_Brand";v="99"" ] "cache-control" => array:1 [ 0 => "no-cache" ] "pragma" => array:1 [ 0 => "no-cache" ] "connection" => array:1 [ 0 => "close" ] "x-real-ip" => array:1 [ 0 => "216.73.216.134" ] "x-forwarded-for" => array:1 [ 0 => "216.73.216.134" ] "x-forwarded-proto" => array:1 [ 0 => "https" ] "x-forwarded-scheme" => array:1 [ 0 => "https" ] "host" => array:1 [ 0 => "ai-care-dict.atmatech.id" ] ]
        request_cookies
        []
        
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