Pemeriksaan TSH Neonatus

Pemeriksaan TSH Neonatus
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Definisi

Kelenjar tiroid merupakan kelenjar yang terdapat pada leher bagian bawah. Kelenjar tiroid bertugas dalam membuat hormon yang diperlukan tubuh untuk menjadi energi, tetap hangat dan menjaga organ bekerja. Hormon tiroid hampir memengaruhi setiap organ dalam tubuh termasuk jantung. Bila tidak memiliki hormon tiroid yang memadai dalam darah, beberapa fungsi tubuh akan lebih bekerja lebih lambat. Sebaliknya, bila memiliki terlalu banyak hormon tiroid, tubuh akan bekerja lebih cepat.

Kelenjar tiroid dikendalikan oleh kelenjar pada otak yang disebut kelenjar pituari. Kelenjar tersebut membentuk TSH. TSH merupakan singkatan dari Thyroid Stimulating Hormon (TSH). TSH berfungsi dalam memberitahu kelenjar tiroid berapa banyak hormon yang dibutuhkan untuk dibuat. TSH yang terlalu tinggi atau terlalu rendah bisa menjadi penanda adanya permasalahan pada kelenjar tiroid.

Pada bayi baru lahir, akan dilakukan pemeriksaan TSH sebagai hipotiroid kongenital pada waktu 48-72 jam sebagai bagian dari pemeriksaan darah awal.

 

Indikasi

Pemeriksaan TSH neonatus dilakukan pada usia bayi 48 sampai 72 jam setelah kelahiran, bersamaan dengan pemeriksaan darah awal. Pemeriksaan ini dilakukan sebagai langkah awal untuk mendiagnosis pencegahan ketidakmampuan perkembangan saraf hingga memaksimalkan perkembangan dari bayi.

Pemeriksaan TSH neonatus sebagai pemeriksaan rutin yang dilakukan sebagai bagian dari pemeriksaan awal untuk membantu diagnosis dan pengobatan pada hipotiroidisme pada kelahiran (hipotiroid kongenital).

 

Kontraindikasi

Pemeriksaan TSH neonatus tidak memiliki kontraindikasi khusus. Pemeriksaan ini merupakan bagian screening bayi anda baru lahir.

 

Persiapan sebelum Pemeriksaan

Tidak ada persiapan khusus sebelum melakukan pemeriksaan TSH neonatus. Pemeriksaan dilakukan pada usia 48 sampai 72 jam setelah kelahiran.

 

Prosedur Pemeriksaan

Pemeriksaan TSH neonatus menggunakan sampel darah. Pada bayi, pengambilan darah dilakukan pada tumit. Petugas laboratorium akan membersihkan permukaan kulit dengan antiseptik atau kapas alkohol (alcohol swab). Kemudian menusukkan jarum dan mengumpulkan darah menggunakan tabung vial. Selanjutnya, darah akan dimasukan ke dalam tabung darah dan diperiksa oleh petugas laboratorium pada mesin khusus. Pemeriksaan ini mungkin akan memakan waktu beberapa hari untuk mendapatkan hasilnya.

 

Nilai Normal dan Abnormal

Nilai normal pemeriksaan TSH bergantung juga dari usia ketika bayi ketika dilakukan pemeriksaan :

  • Saat lahir (Cord blood) : 2.2 hingga 10.7 mU/L
  • Usia 1 sampai 4 hari : 2.7 hingga 26.5 mU/L
  • Usia 4 sampai 30 hari : 1.2 hingga 13.1 mU/L
  • Usia 1 sampai 12 bulan : 0.6 sampai 7.3 mU/L
  • Usia 1 sampai 5 tahun : 0.7-6.6 mU/L

Nilai abnormal pemeriksaan bila hasil pemeriksaan berada dibawah batas bawah normal atau diatas batas normal. Hasil rentang pemeriksaan dapat bervariasi bergantung pada metode laboratorium dimana Anda dilakukan pemeriksaan.

 

Hasil dan Saran (Pemeriksaan Lanjutan)

Hasil pemeriksaan TSH neonatus dengan hasil yang lebih tinggi dari normal dapat menandakan bahwa bayi mengalami hipotiroid kongenital. Pada bayi dengan nilai hasil positif membutuhkan pemeriksaan lebih lanjut untuk memastikan diagnosis dari hipotiroid kongenital. Ketika hipotiroid kongenital sudah terkonfirmasi, Anda akan diarahkan pada endokrinologis untuk penanganan lebih lanjut.

Kondisi ini jarang terjadi tetapi dapat membahayakan nyawa bila dibiarkan tanpa diobati. Pada kondisi ini, bayi akan membutuhkan observasi lebih lanjut paling tidak 4 hari di rumah sakit. Bayi dengan gejala ini memerlukan penanganan khusus untuk terapi lebih lanjut.

 

Konsultasikan ke Dokter yang Tepat

Bila hasil pemeriksaan TSH neonatus menunjukkan hasil tidak normal, Anda dapat berkonsultasi dengan dokter untuk mendapatkan diagnosis dan terapi yang sesuai. Bila diperlukan, Anda juga dapat berkonsultasi dengan dokter spesialis anak terkait kondisi bayi Anda sehingga didapatkan penanganan dan terapi yang tepat.

 

Mau tahu informasi seputar hasil pemeriksaan laboratorium, radiologi, dan lainnya? Cek di sini, ya!

 

 

Writer : dr Kevin Luke
Editor :
  • dr. Monica Salim
Last Updated : Rabu, 13 September 2023 | 08:59

TSH (Thyroid Stimulating Hormon) Test. (2022). Retrieved 22 May 2023, from https://medlineplus.gov/lab-tests/tsh-thyroid-stimulating-hormone-test/

What Is a TSH Test. (2023). Retrieved 22 May 2023, from https://www.webmd.com/women/what-is-tsh-test

Thyroid - Stimulating Hormon (TSH) Levels. (2023). Retrieved 22 May 2023, from https://my.clevelandclinic.org/health/articles/23524-thyroid-stimulating-hormone-tsh-levels

Thyroid - Stimulating Hormon (TSH) Test. (2022). Retrieved 22 May 2023, from https://www.testing.com/tests/thyroid-stimulating-hormone-tsh/

TSH (Thyroid Stimulating Hormon) Test. (2020). Retrieved 22 May 2023, from https://www.healthline.com/health/tsh

What are the Ranges, Symptoms, and Meaning of TSH Levels?. (2023). Retrieved 22 May 2023, from https://www.medicalnewstoday.com/articles/326774

Thyroid Function Testing. (2020). Retrieved 22 May 2023, from https://www.safercare.vic.gov.au/clinical-guidance/neonatal/thyroid-function-tests-for-neonates 

Normal Ranges for Thyroid Function Tests in Infans and Children.. (2023). Retrieved 22 May 2023, from https://www.uptodate.com/contents/image?imageKey=PEDS%2F60095

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      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase9.74msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7264 and `categories`.`deleted_at` is null
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      Hints
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      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase13.83msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7638 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7638
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • related-article.blade.php#8mydatabase9.99msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7608 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7608
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.related-article:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase10.04msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 3530 and `categories`.`deleted_at` is null
      Bindings
      • 0: 3530
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase10.02msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 8011 and `categories`.`deleted_at` is null
      Bindings
      • 0: 8011
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase9.84msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 846 and `categories`.`deleted_at` is null
      Bindings
      • 0: 846
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#11mydatabase970μsselect * from `categories` where `categories`.`id` = 4 and `categories`.`deleted_at` is null limit 1
      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::web.v2.partials.article-popular:11
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase10.02msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 10253 and `categories`.`deleted_at` is null
      Bindings
      • 0: 10253
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase9.69msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 7576 and `categories`.`deleted_at` is null
      Bindings
      • 0: 7576
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase9.75msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 2402 and `categories`.`deleted_at` is null
      Bindings
      • 0: 2402
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • article-popular.blade.php#8mydatabase8.67msselect `categories`.*, `category_post`.`post_id` as `pivot_post_id`, `category_post`.`category_id` as `pivot_category_id`, `category_post`.`created_at` as `pivot_created_at`, `category_post`.`updated_at` as `pivot_updated_at` from `categories` inner join `category_post` on `categories`.`id` = `category_post`.`category_id` where `category_post`.`post_id` = 6422 and `categories`.`deleted_at` is null
      Bindings
      • 0: 6422
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::web.v2.partials.article-popular:8
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:111
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.menu_hover:53
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#54mydatabase1.08msselect * from `categories` where `name` = 'Obat A-Z' and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: Obat A-Z
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.menu_hover:54
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#55mydatabase1.11msselect * from `categories` where `name` = 'Pemeriksaan A-Z' and `categories`.`deleted_at` is null limit 1
      Bindings
      • 0: Pemeriksaan A-Z
      Hints
      • Use SELECT * only if you need all columns from table
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.menu_hover:55
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#156mydatabase3.06msselect * from `videos` where `status` = 1 order by `updated_at` desc limit 1
      Bindings
      • 0: 1
      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::layouts.v2.menu_hover:156
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • menu_hover.blade.php#221mydatabase1.32msselect * from `booklets` where `is_published` = 1 order by `id` desc limit 1
      Bindings
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      Hints
      • Use SELECT * only if you need all columns from table
      Backtrace
      • view::layouts.v2.menu_hover:221
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    • web_layout.blade.php#357mydatabase1.01msselect * from `faqs` limit 1
      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      • LIMIT without ORDER BY causes non-deterministic results, depending on the query execution plan
      Backtrace
      • view::layouts.v2.web_layout:357
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
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      Hints
      • Use SELECT * only if you need all columns from table
      • The SELECT statement has no WHERE clause and could examine many more rows than intended
      Backtrace
      • view::layouts.v2.web_layout:361
      • vendor/laravel/framework/src/Illuminate/Filesystem/Filesystem.php:124
      • vendor/laravel/framework/src/Illuminate/View/Engines/PhpEngine.php:58
      • vendor/livewire/livewire/src/Mechanisms/ExtendBlade/ExtendedCompilerEngine.php:22
      • vendor/laravel/framework/src/Illuminate/View/Engines/CompilerEngine.php:72
    App\Models\Admin\Post
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    App\Models\Admin\Category
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    App\Models\Admin\Tag
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    App\Models\TermPolicy
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    App\Models\Admin\Page
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    App\Models\Admin\Booklet
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